Educational guide
IDENTIFYING DATA 2023_24
Subject PHYSIOLOGY II Code 00106007
Study programme
0106 GRADO EN VETERINARIA
Descriptors Credit. Type Year Period
6 Basic Training First Second
Language
Prerequisites
Department CIENCIAS BIOMEDICAS
Coordinador
ALMAR GALIANA , MARÍAMAR
E-mail malmg@unileon.es
jebayd@unileon.es
mjcueg@unileon.es
jlmaug@unileon.es
gmerp@unileon.es
bsanv@unileon.es
ssanc@unileon.es
bestg@unileon.es
afueb@unileon.es
amilg@unileon.es
sroms@unileon.es
Lecturers
ALMAR GALIANA , MARÍAMAR
BAYÓN DARKISTADE , JOSÉ ENRIQUE
CUEVAS GONZÁLEZ , MARÍA JOSE
MAURIZ GUTIÉRREZ , JOSE LUIS
MERINO PELÁEZ , GRACIA
SAN MIGUEL DE VEGA , BEATRIZ
SÁNCHEZ CAMPOS , SONIA
ESTEBANEZ GONZALEZ , BRISAMAR
FUENTE BARRIENTOS , ALVARO DE LA
MILLAN GARCIA , ALICIA
ROMAN SAGšILLO , SARA SELVA DE
Web http://
General description
Tribunales de Revisión
Tribunal titular
Cargo Departamento Profesor
Presidente CIENCIAS BIOMEDICAS SANCHEZ COLLADO , PILAR
Secretario CIENCIAS BIOMEDICAS ALVEAR ORDENES , ILDEFONSO
Vocal CIENCIAS BIOMEDICAS PEREZ PERTEJO , MARIA YOLANDA
Tribunal suplente
Cargo Departamento Profesor
Presidente CIENCIAS BIOMEDICAS DE PAZ FERNANDEZ , JOSE ANTONIO
Secretario GARCIA ESTRADA , CARLOS
Vocal CIENCIAS BIOMEDICAS ORDOÑEZ PASCUA , CESAR

Competencias
Code  
A19614 106P12 Respect and enforce animal welfare in all professional activities related to animal management.
A19623 106P3 Use basic analytical techniques and interpret their clinical, biological and chemical results.
A19663 106S4 Structure of the eukaryotic cell and its organization in tissues and organs.
A19685 106S6 Excitability and cellular communication.
A19693 106S7 Functioning and regulation of body apparatus and systems.
A19694 106S8 Homeostasis.
B6471 106G1 Analyse, synthesise, solve problems and make decisions in the professional fields of the veterinarian.
B6474 106G4 Communicate the information obtained during the veterinarians professional practice fluently, orally and in writing, with other colleagues, authorities and society in general.
B6476 106G6 Search and manage information related to the veterinarians activity.
B6479 106G9 Demonstrate interest in knowing how to use basic computer tools.
B6480 106G10 Have basic knowledge of a second language, especially in technical aspects related to Veterinary Sciences.
B6481 106G11 Keep the knowledge, skills and attitudes of professional competencies updated through a continuing education process.
C1 CMECES1 That students have demonstrated possession and understanding of knowledge in an area of study that is based on general secondary education, and is usually found at a level that, although supported by advanced textbooks, also includes some aspects that involve knowledge from the cutting edge of their field of study
C2 CMECES2 That students know how to apply their knowledge to their work or vocation in a professional manner and possess the skills that are usually demonstrated through the development and defense of arguments and the resolution of problems within their area of study.
C3 CMECES3 That students have the ability to gather and interpret relevant data (normally within their area of study) to make judgments that include reflection on relevant issues of a social, scientific or ethical nature.
C4 CMECES4 That students can transmit information, ideas, problems and solutions to both a specialised and non-specialised audience
C5 CMECES5 That students have developed those learning skills necessary to undertake further studies with a high degree of autonomy

Learning aims
Competences
To apply the knowledge of physiology in a professional manner and to possess demonstrable skills through developing and sustaining arguments and solving cases B6474
C2
To acquire the ability to gather and interpret relevant data in order to make judgments including reflection on relevant social, scientific or ethical matters B6476
C3
Developing the ability to transmit information, ideas, problems ,and solutions to both specialist and non-specialist audience B6471
B6474
B6476
B6481
C4
Developing learning skills necessary to undertake further studies with a high degree of autonomy B6479
B6480
B6481
C5
To describe the main components of the nervous system and the direction of the flow of information between them A19693
C1
To explain the ionic basis of resting membrane potential, graduate potentials, spatial and temporal summation, and action potential in the neurons, including the nervous integration process and the role of the axon hillock on it, as well as the transmission of the action potential along the axon and synaptically. A19685
B6479
C1
To describe the major classes of neurotransmitters, explaining their release and actions. A19685
B6479
C1
To describe the functional anatomy of the brain and spinal cord, defining the reflex arc and spinal reflexes, particularly the reverse miotatic reflex, withdrawal reflex, and crossed extensor reflex. A19693
C1
C5
To describe the areas of the brain contributing to the control of movement and its basic functions A19623
C1
C5
To describe the different sleep phases and the transition from sleep to wakefulness, including the different types of learning and memory. A19685
B6481
C1
C5
To describe the function of sensory receptors and to explain how they perform this function, including the sensory transduction mechanism and nerve pathways for each of the sensory organs. A19685
C1
C5
To explain the basic functions of the two divisions of the autonomic nervous system, the concept of double innervation, chemical messengers and the types of receptors associated with the autonomic nervous system A19685
A19693
C1
C5
To describe the functional structure of the skeletal muscle cell and muscle contraction, including the cross-bridge cycle and the sliding filament theory. A19663
A19685
C1
To identify the various factors affecting the strength of the muscle contraction, the three types of skeletal muscle fibers and the main differences among them. A19663
A19685
C1
To describe the main features of smooth muscle and cardiac muscle and to compare these muscle types with skeletal muscle A19663
A19685
C1
To perform simulations and evaluation of the function of the transport and signaling systems, action potential and muscle contraction, correctly interpreting the results. A19693
B6479
C1
To describe the links between hypothalamus, adenohypophysis and neurohypophysis, pointing out the function of the trophic hormones in the regulation of the release of other hormones and the importance of feedback. A19693
C1
To describe the synthesis and secretion of growth hormone, thyroid hormones, insulin, glucagon, glucocorticoids, and mineralocorticoids. A19693
C1
C5
To understand the physiological processes associated with the reproduction A19693
C1
C5
To evaluate, either experimentally of using published data, the signaling process of hormones on the physiology of animal organisms. A19614
A19623
C2
C3
To achieve general and specific knowledge about the mechanisms of control of all bodily functions, and in particular the impact of both nervous system and endocrine system control on the functioning of the organism A19693
C1
C2
C3
To consistently use the knowledge acquired on the control function of the different organs and systems, and the corresponding regulatory mechanisms A19693
B6481
C2
C3
To be able of performing simulations of physiological processes and to correctly interpret the results A19693
B6479
C3
C5
To describe the function of the different components of the nervous system facing functional changes. A19693
A19694
C1
To understand and interpret the operation and regulation of the different functional systems A19693
C1
To show a good competence in numerical calculations related to the physiological processes in animals. A19685
A19693
C3

Contents
Topic Sub-topic
Nervous System 1. Excitability. Membrane potential. Action potential. Action potential propagation. Compound action potentials. Registration of action potentials.
2. Synapses. Electrical synapse. Chemical synapses. Neurotransmitters.
3. Skeletal muscle. Structure. Molecular mechanisms of contraction. Excitation-contraction coupling. Mechanics of muscle contraction. Neuromuscular transmission. Smooth muscle. Types of smooth muscle. Characteristics of cardiac muscle.
4. Receptor physiology. Mechanoreception, nociception and termorrecepción. Chemoreception. Fonorrecepción. Photoreception.
5. Functions of the spinal cord. Proprioceptors. Information processing in the spinal cord. Spinal reflexes.
6. Brainstem and cerebral cortex. Balance receptors. Brainstem reflexes. Information processing in the cerebral cortex. Somatosensory cortex. Somatotopía. Supplementary motor cortex, bark promoter and primary motor cortex. Motor pathways.
7. Motor control. Basal ganglia: Structure, circuits and alterations. Alterations. Cerebellum: Functional Divisions, circuits and alterations.
8. Hypothalamus and autonomic nervous system. General organization. Thermoregulation. Characteristics of sympathetic and parasympathetic function. Neurotransmitters. Stress and general adaptation syndrome.
9. Limbic system and higher brain functions. General functions of the amygdala, septum and hippocampus. Reticular formation. Sleep and wakefulness.

LAB 1.- ACTION POTENTIAL

LAB 2.- SKELETAL MUSCLE

LAB 3.- ELECTROMYOGRAPHY

LAB 4.- ELECTROOCULOGRAPHY

LAB 5.- REFLEXES
Endocrine System 10. Hormones. Definition and classification. Mechanisms of hormonal action. Pheromones. Endocrine glands. Pineal gland.
11. Neuroendocrine integration. Hypothalamic hormones pituitary hormones. Adenohypophysis and neurohypophysis. Mechanisms of action. Regulation.
12. Thyroid. Biosynthesis and secretion of thyroid hormones. Actions of thyroid hormones. Regulation.
13. Adrenocortical hormones. Mineralocorticoids. Glucocorticoids. Adrenal androgens. Physiological functions. Regulation.
14. Adrenal medulla. Simpatomedular system. Catecholamines. Hormone actions. Mechanism of action and receptors.
15. Endocrine pancreas. Insulin, glucagon and somatostatin: action and regulation of secretion.
16. Endocrine control of metabolism of calcium and phosphorus. Calcium and phosphorus metabolism. Bone physiology. Parathyroid hormone. Calcitonin. Vitamin D.

LAB 6.- METABOLIC HORMONES
Reproduction 17. Physiology of male reproductive function. Functions of the reproductive organs. Spermatogenesis. Male sex hormones. Physiological actions. Regulation. Environmental factors in reproduction.
18. Physiology of female reproductive function. Functions of the reproductive organs. Female sex hormones. Ovarian cycles. Ovulation. Ovulation rates. Physiological actions of sex hormones.
19. Physiology of pregnancy. Fertilization. Implementation. Functions of the placenta. Types of placenta. Hormonal factors in pregnancy.
20. Physiology of childbirth and lactation. Hormonal factors and mechanical labor. Placenta. Mammary gland. Functional physiology. Lactogenesis. Maintenance of lactation. Ejection. Milk composition.

LAB 7.- OESTRUS
Exercise Physiology 21. Energetics of exercise. Aerobic system and lipid metabolism. Energy storage in the body. Interaction of the aerobic and anaerobic exercise. Recovery from exercise.
22. Hematologic, cardiovascular and respiratory responses to exercise. Muscle adaptations to exercise and training. Biomechanics of locomotion. Evaluation of exercise tolerance.

LAB 8.- ANIMAL HANDLING

Planning
Methodologies  ::  Tests
  Class hours Hours outside the classroom Total hours
Lecture 28 47 75
 
Laboratory practicals 16 4 20
Assignments 2 16 18
Seminars 2 12 14
 
Personal tuition 12 0 12
 
Mixed tests 3 8 11
 
(*)The information in the planning table is for guidance only and does not take into account the heterogeneity of the students.

Methodologies
Methodologies   ::  
  Description
Lecture Lectures supplemented with multimedia presentations, internet, and specific software. Students will also have online tutorials and other interactive blended-learning activities through the institutional teaching portal (Moodle) including the resources and activities for the course.
Laboratory practicals In vivo manipulation of physiological systems. Observation and data collection, getting conclusions after results discussion, and mandatory development of an individual practicals workbook.
Assignments Preparation, in groups, of a work written as an expansion of selected topics included in the course content.
Seminars Discussion and classroom debate as an extension of a particular course topic, as assigned by the teacher.
Personal tuition The student can count on the help of teachers in voluntary tutorials. These tutorials will be held in the teacher's office, upon request by the student via email or the teacher portal.

Personalized attention
 
Personal tuition
Description
The student may count on the help of the teachers in individual or group-based tuition, voluntarily. The tuition sessions will be held in the teacher's office upon request by the student, or through email or using the teaching portal tools.

Personal tuition sessions will take place Monday, Wednesday and Friday from 12 to 14 hours. The group tutoring may take place on Fridays from 12 to 14 hours.

Assessment
  Description Qualification
Lecture There will be a partial examination by the middle of the course. This test will be followed by the final examination covering all topics, except those contents already passed by the student in the midterm exam.

Printed materials or electronic devices (phones, calculators) will not be allowed during the examination excepto in case of explicit permission from the teacher. The proved offense will imply the expulsion of the examination session with zero grade. In any case the internal ULE normative will be applicable (document "Pautas de actuación en los supuestos de plagio, copia o fraude en exámenes o pruebas de evaluación", 29-01-2015)
70 %
Laboratory practicals Assessment of the practical work of the student, including results and discussion, as shown in his individual laboratory workbook. 10 %
Assignments The organization, content, and presentation of written work will be assessed.
Computer-based tools will be used to check for plagiarism, and proportional grading penalties might be applied as a consequence.
10 %
Others Assessment of the participation of the student in seminars and online activities included in the learning management system. 10%
 
Other comments and second call

To pass the subject, students must obtain the minimum scores (5.0) IN EACH AND EVERY ONE of the previous sections. 

· The student who passes any of the theoretical tests will have their grade kept only during the corresponding academic year (June and July sessions). 

 · This subject is part of the Structure and Function Subject, so to pass it it is necessary to have its activities approved, with a minimum grade of 5.0. Students who have reached the minimum value will have their grade retained for subsequent academic years. DIRECTED GROUP WORK (Subject Structure and Function). 

In its evaluation, computer tools are applied to detect plagiarism, and a penalty may occur proportional to its intensity. This could result in not reaching the minimum grade. 

During the evaluation tests, the possession, handling or use of any type of material, means or resource, whether electronic or not (calculators, tablets, mobile phones, computers, watches, etc.), that make copying, plagiarism or fraud. If any irregularity occurs during the evaluation test, the student will fail it.


Sources of information
Access to Recommended Bibliography in the Catalog ULE

Basic

Books:

Bradley G. Klein. Cunningham. Fisiología Veterinaria. Elsevier (6ª edición). 2020 

Dukes´Physiology of Domestic Animals. Wiley (13ª edición). 2015 

Eckert R, Randall D, Augustine G Fisiología Animal. Mecanismos y adaptaciones. McGraw-Hill Interamericana (2ª edición). 1999 

Engelhardt WV, Breves G. Fisiología Veterinaria. Acribia (1ª edición). 2005 

García Sacristán. Fisiología Veterinaria. Tebar Florez (1ª edición). 2018 

Hill RW, Wyse GA, Anderson M. Fisiología Animal. Médica Panamericana (1ª edición). 2006 

Sjaastad OV, Hove K, Sand O. Physiology of Domestic Animals. Scand. Vet. Press (3ª edición). 2016

Enlaces de interés:

http://people.eku.edu/ritchisong/301syl.html/index.htm

http://people.eku.edu/ritchisong/301notes3.htm

http://webvision.umh.es/webvision/spanish/indice.html

Complementary Schmidt Nielsen K, Animal physiology. Adaptation and environment, Cambridge University Press, 1997
Yancey PH, Sherwood L, Klandorf H, , Animal Physiology: from genes to organisms, Belmont, CA: Brooks/Cole, 2013
Raff H, Levitzky M, Fisiología Médica. Un enfoque por aparatos y sistemas, McGraw-Hill, 2013
Pérez D, Arenas C, Melián C, Manual de Endocrinología de Pequeños Animales, Multimédica Ediciones Veterinarias, 2018
Purves D, Augustine GJ, Fitzpatrick D, Hall WC, Lamantia A-S, McNamara JO, Williams SM, Neurociencia, Médica Panamericana, 2015
Kandel ER, Schwartz JH, Jessell TM, Principios de Neurociencia, McGraw-Hill Interamericana, 2001


Recommendations

Subjects that are recommended to be taken simultaneously
ANATOMY II / 00106006
CYTOLOGY AND HISTOLOGY / 00106005

Subjects that it is recommended to have taken before
CHEMISTRY AND PHYSICS_BASICS / 00106001
ANATOMY I / 00106002
PHYSIOLOGY I / 00106003
BIOCHEMISTRY / 00106004