Educational guide
IDENTIFYING DATA 2023_24
Subject VETERINARY PHARMACOLOGY Code 00106019
Study programme
0106 GRADO EN VETERINARIA
Descriptors Credit. Type Year Period
6 Compulsory Second Second
Language
Castellano
Prerequisites
Department CIENCIAS BIOMEDICAS
Coordinador
DÍEZ LIÉBANA , MARÍA JOSÉ
E-mail mjdiel@unileon.es
rdielz@unileon.es
mnferm@unileon.es
jjgarv@unileon.es

jmrodl@unileon.es
amsahp@unileon.es
msiev@unileon.es
clopcd@unileon.es
Lecturers
DÍEZ LÁIZ , RAQUEL
DÍEZ LIÉBANA , MARÍA JOSÉ
FERNÁNDEZ MARTÍNEZ , MARÍA NÉLIDA
GARCÍA VIÉITEZ , JUAN JOSÉ
PUENTE GARCÍA , RAÚL DE LA
RODRÍGUEZ LAGO , JOSÉ MANUEL
SAHAGÚN PRIETO , ANA MARÍA
SIERRA VEGA , MATILDE
LÓPEZ CADENAS , CRISTINA
Web http://
General description General principles of Pharmacokinetics (absorption, distribution, and elimination) and Pharmacodynamics. Receptors, mechanisms of action, interactions and adverse reactions. Study of the most commonly used pharmacological groups for veterinary practice.
Tribunales de Revisión
Tribunal titular
Cargo Departamento Profesor
Presidente CIENCIAS BIOMEDICAS BALAÑA FOUCE , RAFAEL
Secretario CIENCIAS BIOMEDICAS ORDOÑEZ PASCUA , CESAR
Vocal CIENCIAS BIOMEDICAS CUBRIA GARCIA , JUAN CARLOS
Tribunal suplente
Cargo Departamento Profesor
Presidente CIENCIAS BIOMEDICAS TUÑON GONZALEZ , MARIA JESUS
Secretario CIENCIAS BIOMEDICAS PEREZ PERTEJO , MARIA YOLANDA
Vocal CIENCIAS BIOMEDICAS REGUERA TORRES , ROSA MARIA

Competencias
Code  
A19614 106P12 Respect and enforce animal welfare in all professional activities related to animal management.
A19627 106P7 Carry out medical treatments
A19629 106P9 Advise and carry out epidemiological studies and therapeutic and preventive programs in accordance with animal welfare, animal health and public health standards.
A19649 106S27 General pharmacological bases and study of different types of drugs.
B6471 106G1 Analyse, synthesise, solve problems and make decisions in the professional fields of the veterinarian.
B6472 106G2 Work as a team, single or multidisciplinary, and show respect, appreciation and sensitivity to the work of others.
B6473 106G3 Maintain ethical behavior in the exercise of their responsibilities towards the profession and society.
B6481 106G11 Keep the knowledge, skills and attitudes of professional competencies updated through a continuing education process.
C1 CMECES1 That students have demonstrated possession and understanding of knowledge in an area of study that is based on general secondary education, and is usually found at a level that, although supported by advanced textbooks, also includes some aspects that involve knowledge from the cutting edge of their field of study
C2 CMECES2 That students know how to apply their knowledge to their work or vocation in a professional manner and possess the skills that are usually demonstrated through the development and defense of arguments and the resolution of problems within their area of study.
C3 CMECES3 That students have the ability to gather and interpret relevant data (normally within their area of study) to make judgments that include reflection on relevant issues of a social, scientific or ethical nature.
C4 CMECES4 That students can transmit information, ideas, problems and solutions to both a specialised and non-specialised audience
C5 CMECES5 That students have developed those learning skills necessary to undertake further studies with a high degree of autonomy

Learning aims
Competences
Knowledge of the basic principles of Pharmacology, especially in its main aspects of clinical application, in the fields of Pharmacokinetics and Pharmacodynamics A19649
 B6471
B6472
B6481
 C1
C2
C3
C4
C5
Understanding of the mechanisms of action by which drugs exercise their actions and pharmacological effects. A19627
A19629
A19649
 B6472
B6481
 C1
C2
C3
C4
C5
Description of the pharmacological actions of the drugs, indications and contraindications, adverse reactions, posology, the most appropriate routes of administration for each drug and the pharmacological interactions of the most commonly used pharmacological groups in daily veterinary practice. A19614
A19627
A19629
A19649
 B6472
B6473
B6481
 C1
C2
C3
C4
C5
Development of bibliographical searches related to drugs. A19649
 B6472
B6481
 C3
C5

Contents
Topic Sub-topic
I. THEORETICAL PROGRAMME Unit 1.- General concepts of Pharmacology.
Unit 2.- Pharmacokinetics. Absorption: sites and absorption pathways. Bioavailability.
Unit 3.- Distribution of drugs in the body.
Unit 4.- Metabolism of drugs.
Unit 5.- Excretion of drugs. Excretion pathways.
Unit 6.- Pharmacodynamics. Modifying factors of pharmacological activity.
Unit 7.- Drugs acting in the Central Nervous System: anesthetics, analgesics, tranquilizers.
Unit 8.- Steroidal and non-steroidal anti-inflammatory drugs.
Unit 9.- Pharmacology of cardiovascular system (heart and blood).
Unit 10.- Pharmacology of the respiratory system.
Unit 11.- Pharmacology of the digestive and hepatic system. Hypoglycaemic drugs and antithyroid drugs.
Unit 12.- Drugs acting in the reproductive system.
Unit 13.- Antimicrobial drugs. Classification. Antimicrobial resistance. Associations.
Unit 14. Antiseptics and disinfectants.
Unit 15.- Beta-lactam antibiotics.
Unit 16.- Macrolides. Aminoglycosides.
Unit 17.- Tetracyclines. Amphenicoles. Polypeptide antibiotics. Lincosamides.
Unit 18.- Sulfonamides. Quinolones and other antibacterials.
Unit 19.- Antifungal drugs. Antiviral drugs. Antineoplastic drugs.
Unit 20.- Antiparasitic drugs.
II. PRACTICAL PROGRAMME Practice 1.- Review of units used in Pharmacology. Concentrations. Dosage.
Practice 2.- Determination of metabolites of acetylsalicylic acid in urine.
Practice 3.- Experimental evaluation of the neuroleptic action of a phenothiazine compound.
Practice 4.- Pass of drugs through cell membranes.
Practice 5.- Intravenous plasma concentration-time curves. Calculation of pharmacokinetic parameters.
Practice 6.- Extravasal plasma concentration-time curves. Calculation of pharmacokinetic parameters.
Practice 7.- Compared pharmacokinetic in the different animal species.
III. WORK IN GROUPS PROGRAMME Topic 1.- Pharmacology of cell mediators.
Topic 2.- Pharmacology of the autonomous nervous system.

Planning
Methodologies  ::  Tests
  Class hours Hours outside the classroom Total hours
Lecture 30 55 85
 
Laboratory practicals 16 10 26
Assignments 10 25 35
 
Personal tuition 2 0 2
 
Mixed tests 2 0 2
 
(*)The information in the planning table is for guidance only and does not take into account the heterogeneity of the students.

Methodologies
Methodologies   ::  
  Description
Lecture As a general rule, each session will take place in approximately 50 minutes. Multimedia presentations will be used. A summary of each session will be uploaded to the educational platform Ágora
Laboratory practicals Specific practices will be carried out in the Pharmacology laboratory. Specific Pharmacology databases and software will also be used.
Assignments With this methodology, students will carry out and explain work prepared in groups of 4 or 5 students.
Personal tuition Area of Pharmacology (doors 421-424) or through the platform Ágora. For foreign students or disabled people, individual tutoring will be made.

Personalized attention
 
Lecture
Laboratory practicals
Assignments
Description
Area of Pharmacology (doors 421-424) or through the platform Ágora. For foreign students or disabled people, individual tutoring will be made.

Assessment
  Description Qualification
Lecture Attendance and participation will be valued (questions, doubts, etc.). 5 %
Laboratory practicals Practical sessions are compulsory. A continuous evaluation will be made. If the student does not pass the continuous evaluation of the practical contents, a practical test will be carried out. In the event of not passing laboratory practices, the maximum value of final marks in the subject will be 4. 10 %
Assignments Working in groups are compulsory. Participation and attitude of students will be valued. Presentation will also be taken into account. Students will have to pass a written test if they do not work satisfactorily. In the event of not passing this activity, the maximum value of final marks in the subject will be 4. 5 %
Mixed tests Written examination consisting of two parts: test exam (questions with four answers and only one true) and short questions exam. Test exam will be 2/3 of the written examination and short questions 1/3. Examination will be passed with a score equal to or higher than 5. If not, marks achieved in the other sections of the evaluation will not be added, and final marks will be 80 % of the qualification obtained in the written examination. 80 %
 
Other comments and second call

Final marks of the subject in the event of not passing laboratory practices or working groups: the maximum mark will be 4 even if a higher mark has been achieved in the written examination.

In the second call, students will have to take a written exam of that part not passed in the first call, and they will have to obtain a minimum score of 5. If not, the criteria described above will be followed to establish the final marks of the subject.

Documents provided may be reviewed with an anti-plagiarism software. If plagiarism is detected the mark will be 0.0 (fail). The possession, handling or use of any type of material, medium or resource, whether electronic or nonelectronic (calculators, tablets, telephones, computers, etc.), which make it possible to copy, plagiarize or fraud, except for those activities that, under the express indication of the teacher, require its use. If any irregularity occurs during the exams, the exercise will be withdrawn and the student will be asked to leave the exam, and his/her qualification will be 0.0 (fail). In any case, the provisions of the internal regulations of the ULe included in the document "Products of action in cases of plagiarism, copying or fraud in evaluation examinations or tests" (approved by the Standing Committee of the Governing Council on 29/01/2015).

Recording or taking photographs without the prior permission of the teacher is considered a serious offence, to leave the theoretical or practical class and the taking of the measures deemed appropriate.

Sources of information
Access to Recommended Bibliography in the Catalog ULE

Basic Flórez J (director), Farmacología humana, 6a ed. Barcelona: Elsevier Masson, 2014
Botana LM (coordinador), Farmacología veterinaria. Fundamentos y aplicaciones terapéuticas. 2a ed, Buenos Aires: Médica Panamericana, 2022
Brunton LL, Knollmann BC, editors, Goodman & Gilman's The pharmacological basis of Therapeutics, 14th ed. New York: Mc Graw-Hill, 2023
Riviere JE, Papich MG (editors), Veterinary Pharmacology & Therapeutics, Hoboken: Wiley & Sons, 2018

Complementary Sumano H, Ocampo L, Farmacología, Madrid: McGraw-Hill, 2006
Velasco A et al., Farmacología fundamental, Madrid: McGraw-Hill, 2003
Bill R, Medical mathematics and dosage calculations for veterinary professionals, 3rd ed. London: Wiley-Blackwell, 2019
Ritter JM et al., Rang & Dale's Pharmacology, 9th ed. London: Elsevier, 2019
, Real Decreto Legislativo 1/2015, de 24 de julio, por el que se aprueba el texto refundido de la Ley de garantías y uso racional de los medicamentos y productos sanitarios, , BOE nº 177, de 25 de julio de 2015
Maddison J, Page S, Church D, Small animal clinical pharmacology, Edinburgh: Saunders-Elsevier, 2009
Lorenzo P et al., Velázquez Farmacología básica y clínica, 19a ed. Madrid: Médica Panamericana, 2018

Enlaces de interés:

Agencia Española de Medicamentos y Productos Sanitarios https://www.aemps.gob.es/

Agencia Europea del Medicamento https://www.ema.europa.eu

Consultas a Pubmed.gov https://pubmed.ncbi.nlm.nih.gov/

Food Animal ResidueAvoidance Databank (FARAD) http://www.farad.org

Organización Farmacéutica Colegial https://www.farmaceuticos.com/

US Food and DrugAdministration (FDA) https://www.fda.gov/

Recommendations


Subjects that it is recommended to have taken before
PHYSIOLOGY I / 00106003
BIOCHEMISTRY / 00106004
PHYSIOLOGY II / 00106007