Educational guide
IDENTIFYING DATA 2023_24
Subject MOLECULAR PATHOLOGY Code 00206053
Study programme
0206 - GRADO EN BIOLOGÍA
Descriptors Credit. Type Year Period
3 Optional Fourth Second
Language
Castellano
Prerequisites
Department BIOLOGIA MOLECULAR
Coordinador
RODRÍGUEZ OLIVERA , ELÍAS
E-mail erodo@unileon.es
hmarb@unileon.es
nnavm@unileon.es
Lecturers
MARTÍNEZ BLANCO , HONORINA
NAVASA MAYO , NICOLÁS
RODRÍGUEZ OLIVERA , ELÍAS
Web http://
General description Description of the molecular basis as well as the abnormal biochemical processes in human diseases with special reference to :Molecular pathology and biochemistry of the erythrocyte, Molecular pathology of human hemoglobins, Molecular and metabolic failures related with carbohydrates, lipids and aminoacids .
Tribunales de Revisión
Tribunal titular
Cargo Departamento Profesor
Presidente BIOLOGIA MOLECULAR RUA ALLER , FRANCISCO JAVIER
Secretario BIOLOGIA MOLECULAR FERRERO GARCIA , MIGUEL ANGEL
Vocal BIOLOGIA MOLECULAR RODRIGUEZ APARICIO , LEANDRO B.
Tribunal suplente
Cargo Departamento Profesor
Presidente BIOLOGIA MOLECULAR FERNANDEZ CAÑON , JOSE MANUEL
Secretario BIOLOGIA MOLECULAR BARREIRO MENDEZ , CARLOS
Vocal BIOLOGIA MOLECULAR MIÑAMBRES RODRIGUEZ , BALTASAR

Competencias
Code  
A202
A231
A252
B33
B37
B38
B40
C2 CMECES2 That students know how to apply their knowledge to their work or vocation in a professional manner and possess the skills that are usually demonstrated through the development and defense of arguments and the resolution of problems within their area of study.
C3 CMECES3 That students have the ability to gather and interpret relevant data (normally within their area of study) to make judgments that include reflection on relevant issues of a social, scientific or ethical nature.
C4 CMECES4 That students can transmit information, ideas, problems and solutions to both a specialised and non-specialised audience
C5 CMECES5 That students have developed those learning skills necessary to undertake further studies with a high degree of autonomy

Learning aims
Competences
A202
A231
A252
B33
B37
B38
B40
C2
C3
C4
C5

Contents
Topic Sub-topic

Planning
Methodologies  ::  Tests
  Class hours Hours outside the classroom Total hours
Seminars 2 8 10
 
 
Lecture 26 37 63
 
Mixed tests 2 0 2
 
(*)The information in the planning table is for guidance only and does not take into account the heterogeneity of the students.

Methodologies
Methodologies   ::  
  Description
Seminars
Lecture

Personalized attention
 
Lecture
Seminars
Description

Assessment
  Description Qualification
Mixed tests 60%
 
Other comments and second call

Sources of information
Access to Recommended Bibliography in the Catalog ULE

Basic J-M. Gonzalez de Buitrago, E. Arilla, M. Ferreiro, M. Rodriguez-Segade y A. Sanchez-Pozo, Bioquimica Clinica, McGraw Hill-Interamericana, Madrid 1998
Bernard G. Forget and H. Franklin Bunn, Classification of the Disorders of Hemoglobin, CSH, Cold Spring Harb Perspect Med2013;3:a011684
WJ MARSHALL, M LAPSEY, AP DAY, RM AYLING, CLINICAL BIOCHEMISTRY, 3RD ED, CHURCHILL LIVINGSTONE, ELSEVIER, LONDON, 2014
NV BHAGAVAN & CHUNG-EUN HA, ESSENTIALS OF MEDICAL BIOCHEMISTRY WITH CLINICAL CASES 2ª ED, ACADEMIC PRESS, SAN DIEGO, 2015
H.B.Castellanos-Sincoa, et al, Megaloblastic anaemia: Folic acid and vitamin B12 metabolism, Elsevier, RevMedHospGenMéx.2015;78(3):135---143
Ada Hamosh, Online Mendelian Inheritance in Man (OMIM), McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University,
J.M. Gonzales de Buitrago y J.M. Medina Jimenez, Patologia Molecular, McGraw-Hill Interamericana, Madrid 2001
F. Gonzalez Sastre y J. Guinovart, Patologia Molecular, Masson, Barcelona 2003
C.R. Scriver, A.L. Beaudet, W.S. Sly and D. Valle, The Metabolic and Molecular Bases of Inherited Disease, McGraw-Hill, New York 1995
Xuan Shang, et al, Update in the genetics of thalassemia: Whatclinicians need to know, Elsevier, Best Practice & Research Clinical Obstetrics a
D. Sean Froese, Brian Fowler, Matthias R. Baumgartner, Vitamin B12, folate, and the methionine remethylation cycle—biochemistry, pathways, and regulation, Wiley, J Inherit Metab Dis.2019;1–13.

Complementary


Recommendations


Subjects that it is recommended to have taken before
Biochemistry / 00206007
FUNDAMENTAL GENES / 00206010
ANIMAL PHYSIOLOGY I / 00206014
METABOLIC REGULATION / 00206021
PHYSIOPATHOLOGY / 00206037