Educational guide
IDENTIFYING DATA 2023_24
Subject Genomics Code 00208024
Study programme
0208 - GRADO EN BIOTECNOLOGÍA
Descriptors Credit. Type Year Period
4.5 Compulsory Third First
Language
Castellano
Prerequisites
Department BIOLOGIA MOLECULAR
Coordinador
GUTIERREZ GONZALEZ , JUAN JOSE
E-mail jgutg@unileon.es
mcfiec@unileon.es
lesaec@unileon.es
Lecturers
FIERRO CASTRO , MARIA DEL CAMINO
SÁENZ DE MIERA CARNICER , LUIS ENRIQUE
GUTIERREZ GONZALEZ , JUAN JOSE
Web http://
General description This course describes a set of methodologies that enable a massive analysis of genomes in terms of structure and expression and its application to the field of medicine and agriculture.
Tribunales de Revisión
Tribunal titular
Cargo Departamento Profesor
Presidente BIOLOGIA MOLECULAR FERRERO GARCIA , MIGUEL ANGEL
Secretario BIOLOGIA MOLECULAR GARCIA GARCIA , PEDRO
Vocal PRODUCCION ANIMAL ARRANZ SANTOS , JUAN JOSE
Tribunal suplente
Cargo Departamento Profesor
Presidente PRODUCCION ANIMAL FUENTE CRESPO , L. FERNANDO DE LA
Secretario BIOLOGIA MOLECULAR MATEOS DELGADO , LUIS MARIANO
Vocal PRODUCCION ANIMAL BAYON GONZALEZ , YOLANDA

Competencias
Code  
A14043
A14044
A14089
A14090
A14092
A14097
B3765
B3767
B3768
B3787
B3788
B3789
B3808
B3834
B3835
B3836
B3837
B3847
B3848
B3850
B3852
B3855
C1 CMECES1 That students have demonstrated possession and understanding of knowledge in an area of study that is based on general secondary education, and is usually found at a level that, although supported by advanced textbooks, also includes some aspects that involve knowledge from the cutting edge of their field of study
C2 CMECES2 That students know how to apply their knowledge to their work or vocation in a professional manner and possess the skills that are usually demonstrated through the development and defense of arguments and the resolution of problems within their area of study.
C3 CMECES3 That students have the ability to gather and interpret relevant data (normally within their area of study) to make judgments that include reflection on relevant issues of a social, scientific or ethical nature.
C4 CMECES4 That students can transmit information, ideas, problems and solutions to both a specialised and non-specialised audience
C5 CMECES5 That students have developed those learning skills necessary to undertake further studies with a high degree of autonomy

Learning aims
Competences
A14089
A14090
A14092
A14097
 B3767
B3768
B3850
 C1
C2
C3
C4
C5
A14044
A14089
A14092
 B3767
B3768
B3834
B3837
 C1
C2
C3
C4
C5
A14044
A14089
A14090
 B3765
B3767
B3834
B3847
B3848
B3850
B3852
B3855
 C1
C2
C3
C4
C5
A14044
A14089
A14090
A14092
 B3787
B3788
B3789
B3808
B3834
B3835
B3836
B3837
B3850
B3852
 C1
C2
C3
C4
C5
A14043
A14044
A14089
A14092
A14097
 B3787
B3788
B3835
B3837
B3850
 C1
C2
C3
C4
C5

Contents
Topic Sub-topic
INTRODUCTION 1.- Introduction and Origins of Genomics.
2.- Genomes. Generalities. Structure and representation of genomes.
3.- Technical Foundations. Basic application techniques in genomic research.
GENOME ANALYSES 4.- Gene editing techniques.
5.- Sequencing platforms. First, second and third generation.
6.- Assembly and analysis of genomes.
TRANSCRIPTOMICS 7.- Transcriptome assembly and analysis.
8.- Gene expression. RNA-seq y microarrays.
USE OF GENOMICS IN BIOTECHNOLOGY 9.- Markers and Genotyping Techniques.
10.- Genetic maps.
11.- Advanced techniques. QTL, GWAS, Genomic Selection. Genetically modified organisms.

Planning
Methodologies  ::  Tests
  Class hours Hours outside the classroom Total hours
Lecture 28 45 73
 
 
Laboratory practicals 15 22.5 37.5
 
Mixed tests 2 0 2
 
(*)The information in the planning table is for guidance only and does not take into account the heterogeneity of the students.

Methodologies
Methodologies   ::  
  Description
Lecture Lectures in which the teacher explains the contents of the subject. These sessions also include complementary individual or small group activities under the tutelage and guidance of the teacher, as well as continuous evaluation tests.
Laboratory practicals Apply, at a practical level, the theory of this field of knowledge in a given context. Lab work practicing through genomics techniques.

Personalized attention
 
Lecture
Laboratory practicals
Description
The student can count on the help of the teacher in personalized support tutorials. These tutorials will be held in the teacher's office after making an appointment.

Assessment
  Description Qualification
Lecture Attendance and participation in classes will be considered. .
Laboratory practicals The handling of instruments, the attitude in the laboratory and the interpretation of results will be evaluated. .
Mixed tests Theoretical-practical tests will be carried out in which the level of knowledge and the capacity for analysis, the ability to relate different concepts, the clarity and precision in the presentation of knowledge will be evaluated. .
 
Other comments and second call

For the final grade, the following will have been taken into account:

Results of the different theoretical-practical activities carried out during the course (continuos evaluation). It will represent 25% of the final grade. This section will be considered only if at least a score of 5 out of 10 is achieved.

Carrying out of laboratory practices under the supervision of a professor and written presentation of the activities and results obtained during them. It will represent 15% of the final grade.

Global Test (PRUFO) of theoretical-practical content. This test will account for 60% of the final grade, as long as an average grade of at least 4.5 has been achieved.

To pass the class it is necessary to obtain at least 4.5 points out of 10 in the PRUFO and 5 points out of 10 in the final weighted mean.

Students who do not attend all of the practical laboratory classes must undergo a specific test related to the entire content of the practical laboratory classes developed in the PRUFO or in the Extraordinary Test. It is necessary to achieve a grade of 5 out of 10 in that specific test to be able to pass the subject. In this case, this grade will be 15% of the final grade.

The final grade for the course of students who do not achieve a grade of 5 points in the PRUFO will be a maximum of 4.5. The final grade of students who use the extraordinary final test will be governed by the same criteria as those established above .

During the evaluation tests, the possession or use of any type of instrument or material will not be allowed, except for the basic writing material (pen or similar) and those that are expressly authorized by the teacher at the beginning of each test. . If any irregularity occurs during the holding of the exam or evaluation test, for not complying with the above, the exam will be immediately withdrawn, the student will be expelled, and their qualification as a failure, as well as what corresponds to the Guidelines for action in cases of plagiarism, copying or fraud in exams or evaluation tests at the University of León.

Sources of information
Access to Recommended Bibliography in the Catalog ULE

Basic Lesk A.M., Introduction to Genomics, , Oxford University Press 2007
Clark D.P., Molecular Biology, , Academic Cell, 2010
Watson J.D., Baker T.A., Bell S.P., Gan S.P. 2014 , Molecular Biology of the Gene, 7the edition , Cod Spring Harvord
Primrose S.B. and Twyman R.M., Principles of Gene Manipulation and Genomics, , Blackwell Publishing 2006

Complementary


Recommendations

Subjects that are recommended to be taken simultaneously
BIOINFORMATICS / 00208021

Subjects that it is recommended to have taken before
Genetics / 00208013
MOLECULAR GENETICS / 00208018