Educational guide
IDENTIFYING DATA							2023_24
Subject	GENETIC MODIFICATION IN ANIMALS					Code	00208031
Study programme	0208 - GRADO EN BIOTECNOLOGÍA
Descriptors	Credit.	Type	Year	Period
	3	Compulsory	Third	Second
Language	Castellano Ingles
Prerequisites
Department	PRODUCCION ANIMAL
Coordinador	MARQUÉS MARTÍNEZ , MARGARITA				E-mail	mmarm@unileon.es ybayg@unileon.es nmarg@unileon.es
Lecturers	BAYÓN GONZÁLEZ , YOLANDA MARQUÉS MARTÍNEZ , MARGARITA MARTINEZ GARCIA , NICOLE
Web	http://
General description	The subject will cover the key issues and techniques currently used in animal transgenesis and cloning. It will focus on the technical aspects of gene transfer to mammalian cells and to laboratory and domestic animals.
Tribunales de Revisión	Tribunal titular Cargo Departamento Profesor Presidente PRODUCCION ANIMAL FUENTE CRESPO , L. FERNANDO DE LA Secretario PRODUCCION ANIMAL ARRANZ SANTOS , JUAN JOSE Vocal PRODUCCION ANIMAL GONZALO ABASCAL , CARLOS Tribunal suplente Cargo Departamento Profesor Presidente PRODUCCION ANIMAL LOPEZ PUENTE , SECUNDINO Secretario PRODUCCION ANIMAL RANILLA GARCIA , MARIA JOSE Vocal PRODUCCION ANIMAL VALDES SOLIS , CARMEN

Competencias

Code
A14073
A14089
B3837
B3839
B3841
B3846
C1	CMECES1 That students have demonstrated possession and understanding of knowledge in an area of study that is based on general secondary education, and is usually found at a level that, although supported by advanced textbooks, also includes some aspects that involve knowledge from the cutting edge of their field of study
C2	CMECES2 That students know how to apply their knowledge to their work or vocation in a professional manner and possess the skills that are usually demonstrated through the development and defense of arguments and the resolution of problems within their area of study.
C3	CMECES3 That students have the ability to gather and interpret relevant data (normally within their area of study) to make judgments that include reflection on relevant issues of a social, scientific or ethical nature.
C4	CMECES4 That students can transmit information, ideas, problems and solutions to both a specialised and non-specialised audience
C5	CMECES5 That students have developed those learning skills necessary to undertake further studies with a high degree of autonomy

Learning aims

	Competences
	A14073 A14089	B3837 B3839 B3841	C1 C5
	A14073 A14089	B3839 B3841	C2 C5
	A14089	B3837 B3846	C3 C4

Contents

Topic	Sub-topic

Planning

Methodologies  ::  Tests
	Class hours	Hours outside the classroom	Total hours
Lecture	14	28	42
Laboratory practicals	6	1.5	7.5
Practicals using information and communication technologies (ICTs) in computer rooms	1.5	1	2.5
Tutorship of group	7.5	13.5	21
Mixed tests	1	1	2
(*)The information in the planning table is for guidance only and does not take into account the heterogeneity of the students.

Methodologies

Methodologies   ::  

	Description
Lecture
Laboratory practicals
Practicals using information and communication technologies (ICTs) in computer rooms
Tutorship of group

Personalized attention

Lecture Tutorship of group

Description

Assessment

	Description	Qualification
Lecture		Se evaluará junto con las pruebas mixtas. Ver detalles en "Otros comentarios".
Laboratory practicals		20% de la calificación final. Ver detalles en "Otros comentarios".
Tutorship of group		20% de la calificación final. Ver detalles en "Otros comentarios".
Practicals using information and communication technologies (ICTs) in computer rooms		20% de la calificación final. Ver detalles en "Otros comentarios".
Mixed tests		60% de la calificación final (en combinación con la evaluación de la sesión magistral). Ver detalles en "Otros comentarios".
Other comments and second call

Sources of information

Access to Recommended Bibliography in the Catalog ULE

Basic	PEASE, S. & SAUNDERS, T.L, Advanced Protocols for Animal Transgenesis, Springer , 2011 HOUDEBINE, L.M. , Animal Transgenesis and Cloning, Wiley, 2003 KÜHN, R., WURST, W., Gene knockout protocols, Springer. Humana Press., 2009 JOYNER, A.L., Gene targeting. A practical approach., Oxford University Press, 2000. 2ª edición. TWYMAN, R.M., Gene transfer to animal cells, BIOS Scientific Publishers, 2005 BEHRINGER, R., GERTSENSTEIN, M., VINTERSTEN, K.,NAGY, A., Manipulating the Mouse Embryo: A Laboratory Manual, Cold Spring Harbor Laboratory Press, 2013 VERMA, PAUL J., Nuclear Transfer Protocols. Cell Reprogramming and Transgenesis, Springer, 2006 CIBELLI, J., LANZA, R.P., CAMPBELL, K.H.S. & WEST, M.D. , Principles of cloning, Academic Press, 2002 CARTWRIGHT, E.J., Transgenesis Techniques. Principles and Protocols, Springer. Humana Press, 2009 SAUNDERS, T.L., Transgenesis. Methods and Protocols , Springer, 2023 PINKERT, C.A., Transgenic animal technology. A laboratory handbook, Academic Press, 2014
Complementary

Recommendations

Subjects that are recommended to be taken simultaneously

Cell Cultures / 00208028 MOLECULAR GENETIC ENGINEERING / 00208029

Subjects that it is recommended to have taken before

Cell Biology / 00208010 Genetics / 00208013