Educational guide

IDENTIFYING DATA

2023_24

Subject

GENOMICS

Code

01745005

Study programme

1745 - Máster Universitario en Investigación en Biotecnología y Biomedicina

Descriptors

Credit.

Type

Year

Period

Compulsory

First

Second

Language

Prerequisites

Department

PRODUCCION ANIMAL

Coordinador

GUTIÉRREZ GIL , BEATRIZ

E-mail

bgutg@unileon.es
mmarm@unileon.es
jgutg@unileon.es
cgpolp@unileon.es
asuav@unileon.es

Lecturers

GUTIÉRREZ GIL , BEATRIZ

MARQUÉS MARTÍNEZ , MARGARITA

GUTIERREZ GONZALEZ , JUAN JOSE

POLANCO DE LA PUENTE , CARLOS GASPAR

SUAREZ VEGA, AROA

Web

http://

General description

Tribunales de Revisión

Tribunal titular
Cargo	Departamento	Profesor
Presidente	PRODUCCION ANIMAL	ARRANZ SANTOS , JUAN JOSE
Secretario	BIOLOGIA MOLECULAR	GARCIA GARCIA , PEDRO
Vocal	PRODUCCION ANIMAL	FUENTE CRESPO , L. FERNANDO DE LA

Tribunal suplente
Cargo	Departamento	Profesor
Presidente	PRODUCCION ANIMAL	BAYON GONZALEZ , YOLANDA
Secretario	BIOLOGIA MOLECULAR	SAENZ DE MIERA CARNICER , LUIS ENRIQUE
Vocal	BIOLOGIA MOLECULAR	GONZALEZ CORDERO , ANA ISABEL

Competencies

Type A	Code	Competences Specific
	A18950
	A18951
	A18954
	A18955
Type B	Code	Competences Transversal
	B5753
	B5754
	B5755
	B5757
	B5758
	B5761
	B5762
	B5764
	B5765
	B5766
	B5767
	B5768
Type C	Code	Competences Nuclear
	C1
	C2
	C3
	C4
	C5

Learning aims

Competences
A18954	B5753 B5757 B5764 B5765 B5766 B5767	C1 C2 C3 C4
A18950 A18951 A18954	B5753 B5754 B5755 B5757 B5758 B5761 B5764 B5766 B5767 B5768	C2 C3 C4
A18951 A18954 A18955	B5754 B5755 B5758 B5762 B5766 B5767	C1 C2 C4 C5

Contents

Topic	Sub-topic
I. INTRODUCTION	Lecture 1. Introduction to genomics. Genome organisation. Sequencing projects. Next generation sequencing. Databanks. Ensembl and other databases. Lecture 2. Genome management with Galaxy. De novo assembly. Mutation search.
II: GENETIC MARKERS AND GENETIC MAPPING TECHNIQUES	Lecture 3. Genomic markers. High throughput genotyping platforms and main applications. Lecture 4. Basis of gene mapping. Linkage analysis. Genome-wide association analysis or GWAS. Lecture 5. Post-GWAS analyses.
III. BIOINFORMATIC ANALYSIS WORKFLOW OF GENOME SEQUENCING DATA	Lecture 6. Advanced manipulation of DNA sequences obtained by massively parallel sequencing (NGS): Alignments, formats and sequence quality. Variant identification from NGS data.
IV. FUNCIONAL GENOMICS	Lecture 7. Introduction to Epigenomics.

Planning

Methodologies :: Tests
	Class hours	Hours outside the classroom	Total hours
Practicals using information and communication technologies (ICTs) in computer rooms	20	30	50

Personal tuition	2	3	5

Lecture	8	12	20


(*)The information in the planning table is for guidance only and does not take into account the heterogeneity of the students.

Methodologies

Methodologies ::

	Description
Practicals using information and communication technologies (ICTs) in computer rooms	Experimental trials, problems or computer simulations. Students will perform or follow an experimental protocol following the good laboratory practices, the guide of good practices for handling experimental animals and/or genetically manipulated microorganisms. In these sessions, students and the lecturer will discuss the results obtained, analysing their importance and interest.
Personal tuition	Specialised online face-to-face tutorials using educational support platforms. Student assistance in self-study activities. - Analysis of relevant scientific articles on current topics related to the course. - Preparation of written reports, oral presentations or seminars on experimental or bibliographical work. - Carrying out autonomous tasks online or in a computer classroom.
Lecture	Lecture session Presentation or discussion of the contents of the course.

Personalized attention

Description

Assessment

	Description	Qualification
Others	Attendance and active participation in all training activities (classroom and online). Use of bioinformatics tools related to the course and ability to interpret and discuss the results derived from their use. Carrying out, presentation and defence of work.	100%

Other comments and second call
Those tests not passed in the continuous assessment must be passed in the second ordinary exam. Final exam of the subject. The grading system will be in accordance with the stipulations of RD1125/2003. Maximum weighting 70%.

Sources of information

Access to Recommended Bibliography in the Catalog ULE

Basic	, Access to the Recommended Bibliography of the Library Catalogue, , Arthur Lesk, Introduction to Genomics, Oxford University Press, Libro Sarah S. Richardson, Hallam Stevens, Postgenomics: Perspectives on Biology after the Genome, Duke University Press Books, Libro

Complementary

Recommendations